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Laboratorium

Current research topics

  1. Toxicity profiling and ADME of xenobiotics
    Characterisation of the toxicity and absorption, distribution, metabolism, and excretion (ADME) of xenobiotics of current clinical, forensic, pharmaceutical, food safety, and public health relevance.
     

  2. Chemical warfare agents, defence and national security toxicology
    Toxicological characterisation of chemical warfare agents (CWAs) and other hazardous chemicals of relevance to defence and national security, including their toxicity, environmental fate, hydrolysis, and biodegradation.
     

  3. Analytical methods in forensic and regulatory toxicology
    Development, validation, and application of advanced analytical methods for the identification, quantification, and characterisation of toxic substances, consumer products, and hazardous materials for forensic and regulatory toxicology, judicial proceedings, and law-enforcement applications.
     

  4. Evidence handling and standardisation in forensic toxicology
    Development and standardisation of procedures for the collection, handling, securing, preparation, and toxicological analysis of evidential material to support forensic toxicology assessments and expert reporting.
     

  5. Toxicological assessment for medico-legal purposes
    Assessment of toxicity, toxicokinetics, safety, and regulatory aspects of pharmacologically active substances and related products to support medico-legal expert opinions, judicial proceedings, and law-enforcement activities.
     

  6. Ethanol toxicokinetics and breath alcohol testing
    Investigation of ethanol toxicokinetics and factors affecting breath alcohol measurements and their interpretation in forensic toxicology, including studies involving e-cigarette users.
     

  7. Regulatory toxicology, health risk assessment and regulatory intelligence
    Application and development of toxicological health risk assessment and safety assessment strategies for consumer and healthcare products, including pharmaceuticals, cosmetics, food and food-related products, and medical devices. Development of regulatory intelligence approaches to identify emerging toxicological issues, regulatory gaps, evolving requirements, and scientific evidence relevant to regulatory decision-making.
     

  8. New Approach Methodologies (NAMs) in toxicology
    Development, integration, and application of New Approach Methodologies (NAMs) for toxicological hazard identification and risk assessment, including in silico and in chemico approaches and other emerging non-animal methodologies.

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